diff --git a/keyboards/40percentclub/ut47/config.h b/keyboards/40percentclub/ut47/config.h
index 197d6cd181b..9622f58bb32 100644
--- a/keyboards/40percentclub/ut47/config.h
+++ b/keyboards/40percentclub/ut47/config.h
@@ -54,25 +54,3 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 
 /* Enable GNAP matrix serial output */
 #define GNAP_ENABLE
-
-/* USART configuration */
-#ifdef __AVR_ATmega32U4__
-#      define SERIAL_UART_BAUD 9600
-#      define SERIAL_UART_DATA UDR1
-#      define SERIAL_UART_UBRR (F_CPU / (16UL * SERIAL_UART_BAUD) - 1)
-#      define SERIAL_UART_RXD_VECT USART1_RX_vect
-#      define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
-#      define SERIAL_UART_INIT() do { \
-            /* baud rate */ \
-            UBRR1L = SERIAL_UART_UBRR; \
-            /* baud rate */ \
-            UBRR1H = SERIAL_UART_UBRR >> 8; \
-            /* enable TX */ \
-            UCSR1B = _BV(TXEN1); \
-            /* 8-bit data */ \
-            UCSR1C = _BV(UCSZ11) | _BV(UCSZ10); \
-            sei(); \
-        } while(0)
-#   else
-#       error "USART configuration is needed."
-#endif
diff --git a/keyboards/centromere/centromere.c b/keyboards/centromere/centromere.c
index 8800e2ce6ad..269c60fd750 100644
--- a/keyboards/centromere/centromere.c
+++ b/keyboards/centromere/centromere.c
@@ -1,9 +1,5 @@
 #include "centromere.h"
 
-void uart_init(void) {
-	SERIAL_UART_INIT();
-}
-
 void led_init(void) {
 #if MCU == atmega32u2
     setPinOutput(C4); // Set red LED pin as output
@@ -32,7 +28,6 @@ void matrix_init_kb(void) {
 	// put your keyboard start-up code here
 	// runs once when the firmware starts up
 	matrix_init_user();
-	uart_init();
 	led_init();
 }
 
diff --git a/keyboards/centromere/config.h b/keyboards/centromere/config.h
index 0a908f60f9c..e502e2534bc 100644
--- a/keyboards/centromere/config.h
+++ b/keyboards/centromere/config.h
@@ -59,17 +59,9 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 
 //UART settings for communication with the RF microcontroller
 #define SERIAL_UART_BAUD 500000
-#define SERIAL_UART_DATA UDR1
-#define SERIAL_UART_UBRR (F_CPU / (16UL * SERIAL_UART_BAUD) - 1)
-#define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
 #define SERIAL_UART_RXD_PRESENT (UCSR1A & _BV(RXC1))
-#define SERIAL_UART_INIT() do { \
-    	/* baud rate */ \
-    	UBRR1L = SERIAL_UART_UBRR; \
-    	/* baud rate */ \
-    	UBRR1H = SERIAL_UART_UBRR >> 8; \
-    	/* enable TX and RX */ \
-    	UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
-    	/* 8-bit data */ \
-    	UCSR1C = _BV(UCSZ11) | _BV(UCSZ10); \
-  	} while(0)
+#define SERIAL_UART_INIT_CUSTOM       \
+    /* enable TX and RX */            \
+    UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
+    /* 8-bit data */                  \
+    UCSR1C = _BV(UCSZ11) | _BV(UCSZ10);
diff --git a/keyboards/centromere/matrix.c b/keyboards/centromere/matrix.c
index c5fc8db6ce9..5ca083b4350 100644
--- a/keyboards/centromere/matrix.c
+++ b/keyboards/centromere/matrix.c
@@ -26,6 +26,7 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 #include "util.h"
 #include "matrix.h"
 #include "timer.h"
+#include "protocol/serial.h"
 
 #if (MATRIX_COLS <= 8)
 #    define print_matrix_header()  print("\nr/c 01234567\n")
@@ -79,12 +80,11 @@ uint8_t matrix_cols(void) {
 void matrix_init(void) {
 
     matrix_init_quantum();
+    serial_init();
 }
 
 uint8_t matrix_scan(void)
 {
-    SERIAL_UART_INIT();
-
     uint32_t timeout = 0;
 
     //the s character requests the RF remote slave to send the matrix information
diff --git a/keyboards/centromere/rules.mk b/keyboards/centromere/rules.mk
index f08f6e6ebd4..2469d244a64 100644
--- a/keyboards/centromere/rules.mk
+++ b/keyboards/centromere/rules.mk
@@ -31,14 +31,7 @@ MIDI_ENABLE = no 		# MIDI controls
 UNICODE_ENABLE = yes 		# Unicode
 BLUETOOTH_ENABLE = no # Enable Bluetooth with the Adafruit EZ-Key HID
 
-USB = /dev/ttyACM0
-
-# upload: build
-# 	$(CENTROMERE_UPLOAD_COMMAND)
-
-OPT_DEFS += -DCENTROMERE_PROMICRO
-
 # # project specific files
-SRC = matrix.c
+SRC += matrix.c serial_uart.c
 
 LAYOUTS = split_3x5_3 split_3x6_3
diff --git a/keyboards/chimera_ergo/chimera_ergo.c b/keyboards/chimera_ergo/chimera_ergo.c
index 29470f90805..47653c2e4b6 100644
--- a/keyboards/chimera_ergo/chimera_ergo.c
+++ b/keyboards/chimera_ergo/chimera_ergo.c
@@ -1,9 +1,5 @@
 #include "chimera_ergo.h"
 
-void uart_init(void) {
-	SERIAL_UART_INIT();
-}
-
 void led_init(void) {
 	DDRD  |= (1<<1);
 	PORTD |= (1<<1);
@@ -16,16 +12,5 @@ void matrix_init_kb(void) {
 	// put your keyboard start-up code here
 	// runs once when the firmware starts up
 	matrix_init_user();
-	uart_init();
 	led_init();
 }
-
-void matrix_scan_kb(void) {
-	// put your looping keyboard code here
-	// runs every cycle (a lot)
-	matrix_scan_user();
-}
-
-void led_set_kb(uint8_t usb_led) {
-
-}
diff --git a/keyboards/chimera_ergo/config.h b/keyboards/chimera_ergo/config.h
index 262f287a507..4021cdcd507 100644
--- a/keyboards/chimera_ergo/config.h
+++ b/keyboards/chimera_ergo/config.h
@@ -60,19 +60,11 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 
 //UART settings for communication with the RF microcontroller
 #define SERIAL_UART_BAUD 1000000
-#define SERIAL_UART_DATA UDR1
-#define SERIAL_UART_UBRR (F_CPU / (16UL * SERIAL_UART_BAUD) - 1)
-#define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
 #define SERIAL_UART_RXD_PRESENT (UCSR1A & _BV(RXC1))
-#define SERIAL_UART_INIT() do { \
-    	/* baud rate */ \
-    	UBRR1L = SERIAL_UART_UBRR; \
-    	/* baud rate */ \
-    	UBRR1H = SERIAL_UART_UBRR >> 8; \
-    	/* enable TX and RX */ \
-    	UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
-    	/* 8-bit data */ \
-    	UCSR1C = _BV(UCSZ11) | _BV(UCSZ10); \
-  	} while(0)
+#define SERIAL_UART_INIT_CUSTOM       \
+    /* enable TX and RX */            \
+    UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
+    /* 8-bit data */                  \
+    UCSR1C = _BV(UCSZ11) | _BV(UCSZ10);
 
 #endif
diff --git a/keyboards/chimera_ergo/matrix.c b/keyboards/chimera_ergo/matrix.c
index d512a51d973..112b9a40d17 100644
--- a/keyboards/chimera_ergo/matrix.c
+++ b/keyboards/chimera_ergo/matrix.c
@@ -26,6 +26,7 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 #include "util.h"
 #include "matrix.h"
 #include "timer.h"
+#include "protocol/serial.h"
 
 #if (MATRIX_COLS <= 8)
 #    define print_matrix_header()  print("\nr/c 01234567\n")
@@ -88,12 +89,11 @@ uint8_t matrix_cols(void) {
 void matrix_init(void) {
 
     matrix_init_quantum();
+    serial_init();
 }
 
 uint8_t matrix_scan(void)
 {
-    SERIAL_UART_INIT();
-
     uint32_t timeout = 0;
 
     //the s character requests the RF slave to send the matrix
diff --git a/keyboards/chimera_ergo/rules.mk b/keyboards/chimera_ergo/rules.mk
index f37d14107b7..01d5c3c70ce 100644
--- a/keyboards/chimera_ergo/rules.mk
+++ b/keyboards/chimera_ergo/rules.mk
@@ -28,12 +28,5 @@ NKRO_ENABLE = yes		# USB Nkey Rollover - not yet supported in LUFA
 UNICODE_ENABLE = YES 		# Unicode
 # BLUETOOTH_ENABLE = yes # Enable Bluetooth with the Adafruit EZ-Key HID
 
-
-OPT_DEFS += -DCHIMERA_ERGO_PROMICRO
-CHIMERA_ERGO_UPLOAD_COMMAND = while [ ! -r $(USB) ]; do sleep 1; done; \
-                         avrdude -p $(MCU) -c avr109 -U flash:w:$(TARGET).hex -P $(USB)
-
 # # project specific files
-SRC = matrix.c
-
-USB = /dev/ttyACM0
+SRC += matrix.c serial_uart.c
diff --git a/keyboards/chimera_ls/chimera_ls.c b/keyboards/chimera_ls/chimera_ls.c
index 588b02b2d15..f88e9a4f122 100644
--- a/keyboards/chimera_ls/chimera_ls.c
+++ b/keyboards/chimera_ls/chimera_ls.c
@@ -1,9 +1,5 @@
 #include "chimera_ls.h"
 
-void uart_init(void) {
-	SERIAL_UART_INIT();
-}
-
 void led_init(void) {
 	DDRD  |= (1<<1);
 	PORTD |= (1<<1);
@@ -16,16 +12,5 @@ void matrix_init_kb(void) {
 	// put your keyboard start-up code here
 	// runs once when the firmware starts up
 	matrix_init_user();
-	uart_init();
 	led_init();
 }
-
-void matrix_scan_kb(void) {
-	// put your looping keyboard code here
-	// runs every cycle (a lot)
-	matrix_scan_user();
-}
-
-void led_set_kb(uint8_t usb_led) {
-
-}
diff --git a/keyboards/chimera_ls/config.h b/keyboards/chimera_ls/config.h
index 87e9196095a..d9c14a3fce6 100644
--- a/keyboards/chimera_ls/config.h
+++ b/keyboards/chimera_ls/config.h
@@ -60,19 +60,11 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 
 //UART settings for communication with the RF microcontroller
 #define SERIAL_UART_BAUD 1000000
-#define SERIAL_UART_DATA UDR1
-#define SERIAL_UART_UBRR (F_CPU / (16UL * SERIAL_UART_BAUD) - 1)
-#define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
 #define SERIAL_UART_RXD_PRESENT (UCSR1A & _BV(RXC1))
-#define SERIAL_UART_INIT() do { \
-    	/* baud rate */ \
-    	UBRR1L = SERIAL_UART_UBRR; \
-    	/* baud rate */ \
-    	UBRR1H = SERIAL_UART_UBRR >> 8; \
-    	/* enable TX and RX */ \
-    	UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
-    	/* 8-bit data */ \
-    	UCSR1C = _BV(UCSZ11) | _BV(UCSZ10); \
-  	} while(0)
+#define SERIAL_UART_INIT_CUSTOM       \
+    /* enable TX and RX */            \
+    UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
+    /* 8-bit data */                  \
+    UCSR1C = _BV(UCSZ11) | _BV(UCSZ10);
 
 #endif
diff --git a/keyboards/chimera_ls/matrix.c b/keyboards/chimera_ls/matrix.c
index 72fe4413704..7208d971e12 100644
--- a/keyboards/chimera_ls/matrix.c
+++ b/keyboards/chimera_ls/matrix.c
@@ -26,6 +26,7 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 #include "util.h"
 #include "matrix.h"
 #include "timer.h"
+#include "protocol/serial.h"
 
 #if (MATRIX_COLS <= 8)
 #    define print_matrix_header()  print("\nr/c 01234567\n")
@@ -92,12 +93,11 @@ uint8_t matrix_cols(void) {
 
 void matrix_init(void) {
     matrix_init_quantum();
+    serial_init();
 }
 
 uint8_t matrix_scan(void)
 {
-    SERIAL_UART_INIT();
-
     uint32_t timeout = 0;
 
     //the s character requests the RF slave to send the matrix
diff --git a/keyboards/chimera_ls/rules.mk b/keyboards/chimera_ls/rules.mk
index 162e06aaf75..536e6053a16 100644
--- a/keyboards/chimera_ls/rules.mk
+++ b/keyboards/chimera_ls/rules.mk
@@ -28,14 +28,8 @@ NKRO_ENABLE = yes		# USB Nkey Rollover - not yet supported in LUFA
 UNICODE_ENABLE = YES 		# Unicode
 # BLUETOOTH_ENABLE = yes # Enable Bluetooth with the Adafruit EZ-Key HID
 
-USB = /dev/ttyACM0
-
-OPT_DEFS += -DCHIMERA_LS_PROMICRO
-CHIMERA_LS_UPLOAD_COMMAND = while [ ! -r $(USB) ]; do sleep 1; done; \
-                         avrdude -p $(MCU) -c avr109 -U flash:w:$(TARGET).hex -P $(USB)
-
 # project specific files
-SRC = matrix.c
+SRC += matrix.c serial_uart.c
 
 LAYOUTS = ortho_4x12
 
diff --git a/keyboards/chimera_ortho/chimera_ortho.c b/keyboards/chimera_ortho/chimera_ortho.c
index 2a602cf2f7c..2cdc3d9331d 100644
--- a/keyboards/chimera_ortho/chimera_ortho.c
+++ b/keyboards/chimera_ortho/chimera_ortho.c
@@ -1,9 +1,5 @@
 #include "chimera_ortho.h"
 
-void uart_init(void) {
-	SERIAL_UART_INIT();
-}
-
 void led_init(void) {
 	DDRD  |= (1<<1);
 	PORTD |= (1<<1);
@@ -16,16 +12,5 @@ void matrix_init_kb(void) {
 	// put your keyboard start-up code here
 	// runs once when the firmware starts up
 	matrix_init_user();
-	uart_init();
 	led_init();
 }
-
-void matrix_scan_kb(void) {
-	// put your looping keyboard code here
-	// runs every cycle (a lot)
-	matrix_scan_user();
-}
-
-void led_set_kb(uint8_t usb_led) {
-
-}
diff --git a/keyboards/chimera_ortho/config.h b/keyboards/chimera_ortho/config.h
index 4ce70e68ba3..b103589879a 100644
--- a/keyboards/chimera_ortho/config.h
+++ b/keyboards/chimera_ortho/config.h
@@ -60,19 +60,11 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 
 //UART settings for communication with the RF microcontroller
 #define SERIAL_UART_BAUD 1000000
-#define SERIAL_UART_DATA UDR1
-#define SERIAL_UART_UBRR (F_CPU / (16UL * SERIAL_UART_BAUD) - 1)
-#define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
 #define SERIAL_UART_RXD_PRESENT (UCSR1A & _BV(RXC1))
-#define SERIAL_UART_INIT() do { \
-    	/* baud rate */ \
-    	UBRR1L = SERIAL_UART_UBRR; \
-    	/* baud rate */ \
-    	UBRR1H = SERIAL_UART_UBRR >> 8; \
-    	/* enable TX and RX */ \
-    	UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
-    	/* 8-bit data */ \
-    	UCSR1C = _BV(UCSZ11) | _BV(UCSZ10); \
-  	} while(0)
+#define SERIAL_UART_INIT_CUSTOM       \
+    /* enable TX and RX */            \
+    UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
+    /* 8-bit data */                  \
+    UCSR1C = _BV(UCSZ11) | _BV(UCSZ10);
 
 #endif
diff --git a/keyboards/chimera_ortho/matrix.c b/keyboards/chimera_ortho/matrix.c
index dc38ba74f86..eb2f18473ef 100644
--- a/keyboards/chimera_ortho/matrix.c
+++ b/keyboards/chimera_ortho/matrix.c
@@ -26,6 +26,7 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 #include "util.h"
 #include "matrix.h"
 #include "timer.h"
+#include "protocol/serial.h"
 
 #if (MATRIX_COLS <= 8)
 #    define print_matrix_header()  print("\nr/c 01234567\n")
@@ -78,12 +79,11 @@ uint8_t matrix_cols(void) {
 void matrix_init(void) {
 
     matrix_init_quantum();
+    serial_init();
 }
 
 uint8_t matrix_scan(void)
 {
-    SERIAL_UART_INIT();
-
     uint32_t timeout = 0;
 
     //the s character requests the RF slave to send the matrix
diff --git a/keyboards/chimera_ortho/rules.mk b/keyboards/chimera_ortho/rules.mk
index bf341ab5dd0..e3bbaa39d41 100644
--- a/keyboards/chimera_ortho/rules.mk
+++ b/keyboards/chimera_ortho/rules.mk
@@ -28,11 +28,5 @@ NKRO_ENABLE = yes		# USB Nkey Rollover - not yet supported in LUFA
 UNICODE_ENABLE = YES 		# Unicode
 # BLUETOOTH_ENABLE = yes # Enable Bluetooth with the Adafruit EZ-Key HID
 
-USB = /dev/ttyACM0
-
-OPT_DEFS += -DCHIMERA_ORTHO_PROMICRO
-CHIMERA_ORTHO_UPLOAD_COMMAND = while [ ! -r $(USB) ]; do sleep 1; done; \
-                         avrdude -p $(MCU) -c avr109 -U flash:w:$(TARGET).hex -P $(USB)
-
 # project specific files
-SRC = matrix.c
+SRC += matrix.c serial_uart.c
diff --git a/keyboards/chimera_ortho_plus/chimera_ortho_plus.c b/keyboards/chimera_ortho_plus/chimera_ortho_plus.c
index 1972f2a9c33..6d87ed7053f 100644
--- a/keyboards/chimera_ortho_plus/chimera_ortho_plus.c
+++ b/keyboards/chimera_ortho_plus/chimera_ortho_plus.c
@@ -1,9 +1,5 @@
 #include "chimera_ortho_plus.h"
 
-void uart_init(void) {
-	SERIAL_UART_INIT();
-}
-
 void led_init(void) {
     setPinOutput(D1);
     setPinOutput(F4);
@@ -18,6 +14,5 @@ void matrix_init_kb(void) {
 	// put your keyboard start-up code here
 	// runs once when the firmware starts up
 	matrix_init_user();
-	uart_init();
 	led_init();
 }
diff --git a/keyboards/chimera_ortho_plus/config.h b/keyboards/chimera_ortho_plus/config.h
index e060e196aa9..4b12796e95b 100644
--- a/keyboards/chimera_ortho_plus/config.h
+++ b/keyboards/chimera_ortho_plus/config.h
@@ -59,17 +59,9 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 
 //UART settings for communication with the RF microcontroller
 #define SERIAL_UART_BAUD 1000000
-#define SERIAL_UART_DATA UDR1
-#define SERIAL_UART_UBRR (F_CPU / (16UL * SERIAL_UART_BAUD) - 1)
-#define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
 #define SERIAL_UART_RXD_PRESENT (UCSR1A & _BV(RXC1))
-#define SERIAL_UART_INIT() do { \
-    	/* baud rate */ \
-    	UBRR1L = SERIAL_UART_UBRR; \
-    	/* baud rate */ \
-    	UBRR1H = SERIAL_UART_UBRR >> 8; \
-    	/* enable TX and RX */ \
-    	UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
-    	/* 8-bit data */ \
-    	UCSR1C = _BV(UCSZ11) | _BV(UCSZ10); \
-  	} while(0)
+#define SERIAL_UART_INIT_CUSTOM       \
+    /* enable TX and RX */            \
+    UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
+    /* 8-bit data */                  \
+    UCSR1C = _BV(UCSZ11) | _BV(UCSZ10);
diff --git a/keyboards/chimera_ortho_plus/matrix.c b/keyboards/chimera_ortho_plus/matrix.c
index ed6eac2b093..2bdc97991cf 100644
--- a/keyboards/chimera_ortho_plus/matrix.c
+++ b/keyboards/chimera_ortho_plus/matrix.c
@@ -26,6 +26,7 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 #include "util.h"
 #include "matrix.h"
 #include "timer.h"
+#include "protocol/serial.h"
 
 #if (MATRIX_COLS <= 8)
 #    define print_matrix_header()  print("\nr/c 01234567\n")
@@ -78,12 +79,11 @@ uint8_t matrix_cols(void) {
 void matrix_init(void) {
 
     matrix_init_quantum();
+    serial_init();
 }
 
 uint8_t matrix_scan(void)
 {
-    SERIAL_UART_INIT();
-
     uint32_t timeout = 0;
 
     //the s character requests the RF slave to send the matrix
diff --git a/keyboards/chimera_ortho_plus/rules.mk b/keyboards/chimera_ortho_plus/rules.mk
index 2dd6c3e1f04..fec1bef7308 100644
--- a/keyboards/chimera_ortho_plus/rules.mk
+++ b/keyboards/chimera_ortho_plus/rules.mk
@@ -33,4 +33,4 @@ UNICODE_ENABLE = yes
 CUSTOM_MATRIX = yes
 
 # project specific files
-SRC = matrix.c
+SRC += matrix.c serial_uart.c
diff --git a/keyboards/comet46/comet46.c b/keyboards/comet46/comet46.c
index 0710b8e330d..7c7edba93e1 100644
--- a/keyboards/comet46/comet46.c
+++ b/keyboards/comet46/comet46.c
@@ -1,22 +1 @@
 #include "comet46.h"
-
-void uart_init(void) {
-	SERIAL_UART_INIT();
-}
-
-void matrix_init_kb(void) {
-	// put your keyboard start-up code here
-	// runs once when the firmware starts up
-	matrix_init_user();
-	uart_init();
-}
-
-void matrix_scan_kb(void) {
-	// put your looping keyboard code here
-	// runs every cycle (a lot)
-	matrix_scan_user();
-}
-
-void led_set_kb(uint8_t usb_led) {
-
-}
diff --git a/keyboards/comet46/config.h b/keyboards/comet46/config.h
index d50224eb60f..5ae026f9238 100644
--- a/keyboards/comet46/config.h
+++ b/keyboards/comet46/config.h
@@ -66,19 +66,11 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 
 //UART settings for communication with the RF microcontroller
 #define SERIAL_UART_BAUD 1000000
-#define SERIAL_UART_DATA UDR1
-#define SERIAL_UART_UBRR (F_CPU / (16UL * SERIAL_UART_BAUD) - 1)
-#define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
 #define SERIAL_UART_RXD_PRESENT (UCSR1A & _BV(RXC1))
-#define SERIAL_UART_INIT() do { \
-    	/* baud rate */ \
-    	UBRR1L = SERIAL_UART_UBRR; \
-    	/* baud rate */ \
-    	UBRR1H = SERIAL_UART_UBRR >> 8; \
-    	/* enable TX and RX */ \
-    	UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
-    	/* 8-bit data */ \
-    	UCSR1C = _BV(UCSZ11) | _BV(UCSZ10); \
-  	} while(0)
+#define SERIAL_UART_INIT_CUSTOM       \
+    /* enable TX and RX */            \
+    UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
+    /* 8-bit data */                  \
+    UCSR1C = _BV(UCSZ11) | _BV(UCSZ10);
 
 #endif
diff --git a/keyboards/comet46/matrix.c b/keyboards/comet46/matrix.c
index dc38ba74f86..eb2f18473ef 100644
--- a/keyboards/comet46/matrix.c
+++ b/keyboards/comet46/matrix.c
@@ -26,6 +26,7 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 #include "util.h"
 #include "matrix.h"
 #include "timer.h"
+#include "protocol/serial.h"
 
 #if (MATRIX_COLS <= 8)
 #    define print_matrix_header()  print("\nr/c 01234567\n")
@@ -78,12 +79,11 @@ uint8_t matrix_cols(void) {
 void matrix_init(void) {
 
     matrix_init_quantum();
+    serial_init();
 }
 
 uint8_t matrix_scan(void)
 {
-    SERIAL_UART_INIT();
-
     uint32_t timeout = 0;
 
     //the s character requests the RF slave to send the matrix
diff --git a/keyboards/comet46/rules.mk b/keyboards/comet46/rules.mk
index 2aaa5483c80..1f22b7535eb 100644
--- a/keyboards/comet46/rules.mk
+++ b/keyboards/comet46/rules.mk
@@ -28,8 +28,8 @@ NKRO_ENABLE = yes		# USB Nkey Rollover - not yet supported in LUFA
 UNICODE_ENABLE = YES 		# Unicode
 # BLUETOOTH_ENABLE = yes # Enable Bluetooth with the Adafruit EZ-Key HID
 
-USB = /dev/ttyACM0
 # project specific files
 SRC += matrix.c \
        i2c.c \
-       ssd1306.c
+       ssd1306.c \
+       serial_uart.c
diff --git a/keyboards/dichotomy/config.h b/keyboards/dichotomy/config.h
index 05210198c8b..0cdaf776b46 100644
--- a/keyboards/dichotomy/config.h
+++ b/keyboards/dichotomy/config.h
@@ -60,19 +60,11 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 
 //UART settings for communication with the RF microcontroller
 #define SERIAL_UART_BAUD 1000000
-#define SERIAL_UART_DATA UDR1
-#define SERIAL_UART_UBRR (F_CPU / (16UL * SERIAL_UART_BAUD) - 1)
-#define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
 #define SERIAL_UART_RXD_PRESENT (UCSR1A & _BV(RXC1))
-#define SERIAL_UART_INIT() do { \
-    	/* baud rate */ \
-    	UBRR1L = SERIAL_UART_UBRR; \
-    	/* baud rate */ \
-    	UBRR1H = SERIAL_UART_UBRR >> 8; \
-    	/* enable TX and RX */ \
-    	UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
-    	/* 8-bit data */ \
-    	UCSR1C = _BV(UCSZ11) | _BV(UCSZ10); \
-  	} while(0)
+#define SERIAL_UART_INIT_CUSTOM       \
+    /* enable TX and RX */            \
+    UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
+    /* 8-bit data */                  \
+    UCSR1C = _BV(UCSZ11) | _BV(UCSZ10);
 
 #endif
diff --git a/keyboards/dichotomy/dichotomy.c b/keyboards/dichotomy/dichotomy.c
index b94030a3763..967d7e603ce 100755
--- a/keyboards/dichotomy/dichotomy.c
+++ b/keyboards/dichotomy/dichotomy.c
@@ -1,12 +1,7 @@
 #include "dichotomy.h"
 
-void uart_init(void) {
-	SERIAL_UART_INIT();
-}
-
 void pointing_device_task(void){
 	/*report_mouse_t currentReport = {};
-    SERIAL_UART_INIT();
     uint32_t timeout = 0;
 
     //the m character requests the RF slave to send the mouse report
@@ -77,16 +72,5 @@ void matrix_init_kb(void) {
 	// put your keyboard start-up code here
 	// runs once when the firmware starts up
 	matrix_init_user();
-	uart_init();
 	led_init();
 }
-
-void matrix_scan_kb(void) {
-	// put your looping keyboard code here
-	// runs every cycle (a lot)
-	matrix_scan_user();
-}
-
-void led_set_kb(uint8_t usb_led) {
-
-}
diff --git a/keyboards/dichotomy/matrix.c b/keyboards/dichotomy/matrix.c
index d93889e6ad4..2400753cc1e 100755
--- a/keyboards/dichotomy/matrix.c
+++ b/keyboards/dichotomy/matrix.c
@@ -29,6 +29,7 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 #include "dichotomy.h"
 #include "pointing_device.h"
 #include "report.h"
+#include "protocol/serial.h"
 
 #if (MATRIX_COLS <= 8)
 #    define print_matrix_header()  print("\nr/c 01234567\n")
@@ -93,11 +94,11 @@ uint8_t matrix_cols(void) {
 
 void matrix_init(void) {
     matrix_init_quantum();
+    serial_init();
 }
 
 uint8_t matrix_scan(void)
 {
-    SERIAL_UART_INIT();
     //xprintf("\r\nTRYING TO SCAN");
 
     uint32_t timeout = 0;
diff --git a/keyboards/dichotomy/rules.mk b/keyboards/dichotomy/rules.mk
index 14dc4743591..d6f98125eed 100755
--- a/keyboards/dichotomy/rules.mk
+++ b/keyboards/dichotomy/rules.mk
@@ -29,14 +29,5 @@ NKRO_ENABLE = yes		# USB Nkey Rollover - not yet supported in LUFA
 UNICODE_ENABLE = YES 		# Unicode
 # BLUETOOTH_ENABLE = yes # Enable Bluetooth with the Adafruit EZ-Key HID
 
-USB = /dev/ttyACM0
-
-OPT_DEFS += -DDICHOTOMY_PROMICRO
-DICHOTOMY_UPLOAD_COMMAND = while [ ! -r $(USB) ]; do sleep 1; done; \
-                         avrdude -p $(MCU) -c avr109 -U flash:w:$(TARGET).hex -P $(USB)
-
 # # project specific files
-SRC = matrix.c
-
-#upload: build
-#	$(DICHOTOMY_UPLOAD_COMMAND)
+SRC += matrix.c serial_uart.c
diff --git a/keyboards/hhkb/ansi/config.h b/keyboards/hhkb/ansi/config.h
index 5e4fece17df..78fe0c47aeb 100644
--- a/keyboards/hhkb/ansi/config.h
+++ b/keyboards/hhkb/ansi/config.h
@@ -52,27 +52,20 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 #define SUART_IN_PIN    PIND
 #define SUART_IN_BIT    1
 
-#ifdef __AVR_ATmega32U4__
-    #define SERIAL_UART_BAUD        115200
-    #define SERIAL_UART_DATA        UDR1
-    #define SERIAL_UART_UBRR        ((F_CPU/(16.0*SERIAL_UART_BAUD)-1+0.5))
-    #define SERIAL_UART_RXD_VECT    USART1_RX_vect
-    #define SERIAL_UART_TXD_READY   (UCSR1A&(1<<UDRE1))
-    #define SERIAL_UART_INIT()      do { \
-        UBRR1L = (uint8_t) SERIAL_UART_UBRR;       /* baud rate */ \
-        UBRR1H = ((uint16_t)SERIAL_UART_UBRR>>8);  /* baud rate */ \
-        UCSR1B |= (1<<RXCIE1) | (1<<RXEN1); /* RX interrupt, RX: enable */ \
-        UCSR1B |= (0<<TXCIE1) | (1<<TXEN1); /* TX interrupt, TX: enable */ \
-        UCSR1C |= (0<<UPM11) | (0<<UPM10);  /* parity: none(00), even(01), odd(11) */ \
-        UCSR1D |= (0<<RTSEN) | (0<<CTSEN);  /* RTS, CTS(no flow control by hardware) */ \
-        DDRD |= (1<<5); PORTD &= ~(1<<5);   /* RTS for flow control by firmware */ \
-        sei(); \
-    } while(0)
-    #define SERIAL_UART_RTS_LO()    do { PORTD &= ~(1<<5); } while (0)
-    #define SERIAL_UART_RTS_HI()    do { PORTD |=  (1<<5); } while (0)
-#else
-    #error "USART configuration is needed."
-#endif
+#define SERIAL_UART_BAUD 115200
+#define SERIAL_UART_INIT_CUSTOM                 \
+    /* RX interrupt, RX: enable */              \
+    UCSR1B |= (1<<RXCIE1) | (1<<RXEN1);         \
+    /* TX interrupt, TX: enable */              \
+    UCSR1B |= (0<<TXCIE1) | (1<<TXEN1);         \
+    /* parity: none(00), even(01), odd(11) */   \
+    UCSR1C |= (0<<UPM11) | (0<<UPM10);          \
+    /* RTS, CTS(no flow control by hardware) */ \
+    UCSR1D |= (0<<RTSEN) | (0<<CTSEN);          \
+    /* RTS for flow control by firmware */      \
+    DDRD |= (1<<5); PORTD &= ~(1<<5);
+#define SERIAL_UART_RTS_LO() do { PORTD &= ~(1<<5); } while (0)
+#define SERIAL_UART_RTS_HI() do { PORTD |=  (1<<5); } while (0)
 
 /* power control of key switch board */
 #define HHKB_POWER_SAVING
diff --git a/keyboards/hhkb/jp/config.h b/keyboards/hhkb/jp/config.h
index c06c554b2a5..22ac6aa6235 100644
--- a/keyboards/hhkb/jp/config.h
+++ b/keyboards/hhkb/jp/config.h
@@ -52,27 +52,20 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 #define SUART_IN_PIN    PIND
 #define SUART_IN_BIT    1
 
-#ifdef __AVR_ATmega32U4__
-    #define SERIAL_UART_BAUD        115200
-    #define SERIAL_UART_DATA        UDR1
-    #define SERIAL_UART_UBRR        ((F_CPU/(16.0*SERIAL_UART_BAUD)-1+0.5))
-    #define SERIAL_UART_RXD_VECT    USART1_RX_vect
-    #define SERIAL_UART_TXD_READY   (UCSR1A&(1<<UDRE1))
-    #define SERIAL_UART_INIT()      do { \
-        UBRR1L = (uint8_t) SERIAL_UART_UBRR;       /* baud rate */ \
-        UBRR1H = ((uint16_t)SERIAL_UART_UBRR>>8);  /* baud rate */ \
-        UCSR1B |= (1<<RXCIE1) | (1<<RXEN1); /* RX interrupt, RX: enable */ \
-        UCSR1B |= (0<<TXCIE1) | (1<<TXEN1); /* TX interrupt, TX: enable */ \
-        UCSR1C |= (0<<UPM11) | (0<<UPM10);  /* parity: none(00), even(01), odd(11) */ \
-        UCSR1D |= (0<<RTSEN) | (0<<CTSEN);  /* RTS, CTS(no flow control by hardware) */ \
-        DDRD |= (1<<5); PORTD &= ~(1<<5);   /* RTS for flow control by firmware */ \
-        sei(); \
-    } while(0)
-    #define SERIAL_UART_RTS_LO()    do { PORTD &= ~(1<<5); } while (0)
-    #define SERIAL_UART_RTS_HI()    do { PORTD |=  (1<<5); } while (0)
-#else
-    #error "USART configuration is needed."
-#endif
+#define SERIAL_UART_BAUD 115200
+#define SERIAL_UART_INIT_CUSTOM                 \
+    /* RX interrupt, RX: enable */              \
+    UCSR1B |= (1<<RXCIE1) | (1<<RXEN1);         \
+    /* TX interrupt, TX: enable */              \
+    UCSR1B |= (0<<TXCIE1) | (1<<TXEN1);         \
+    /* parity: none(00), even(01), odd(11) */   \
+    UCSR1C |= (0<<UPM11) | (0<<UPM10);          \
+    /* RTS, CTS(no flow control by hardware) */ \
+    UCSR1D |= (0<<RTSEN) | (0<<CTSEN);          \
+    /* RTS for flow control by firmware */      \
+    DDRD |= (1<<5); PORTD &= ~(1<<5);
+#define SERIAL_UART_RTS_LO() do { PORTD &= ~(1<<5); } while (0)
+#define SERIAL_UART_RTS_HI() do { PORTD |=  (1<<5); } while (0)
 
 /* power control of key switch board */
 #define HHKB_POWER_SAVING
diff --git a/keyboards/honeycomb/config.h b/keyboards/honeycomb/config.h
index 4991c8a0eaf..725f9490cbe 100755
--- a/keyboards/honeycomb/config.h
+++ b/keyboards/honeycomb/config.h
@@ -48,17 +48,9 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 
 //UART settings for communication with the RF microcontroller
 #define SERIAL_UART_BAUD 1000000
-#define SERIAL_UART_DATA UDR1
-#define SERIAL_UART_UBRR (F_CPU / (16UL * SERIAL_UART_BAUD) - 1)
-#define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
 #define SERIAL_UART_RXD_PRESENT (UCSR1A & _BV(RXC1))
-#define SERIAL_UART_INIT() do { \
-  /* baud rate */ \
-  UBRR1L = SERIAL_UART_UBRR; \
-  /* baud rate */ \
-  UBRR1H = SERIAL_UART_UBRR >> 8; \
-  /* enable TX and RX */ \
-  UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
-  /* 8-bit data */ \
-  UCSR1C = _BV(UCSZ11) | _BV(UCSZ10); \
-} while(0)
+#define SERIAL_UART_INIT_CUSTOM       \
+    /* enable TX and RX */            \
+    UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
+    /* 8-bit data */                  \
+    UCSR1C = _BV(UCSZ11) | _BV(UCSZ10);
diff --git a/keyboards/honeycomb/honeycomb.c b/keyboards/honeycomb/honeycomb.c
index add4af15365..1254196d39c 100755
--- a/keyboards/honeycomb/honeycomb.c
+++ b/keyboards/honeycomb/honeycomb.c
@@ -2,13 +2,8 @@
 #include "pointing_device.h"
 #include "report.h"
 
-void uart_init(void) {
-	SERIAL_UART_INIT();
-}
-
 void pointing_device_task(void){
 	/*report_mouse_t currentReport = {};
-    SERIAL_UART_INIT();
     uint32_t timeout = 0;
 
     //the m character requests the RF slave to send the mouse report
@@ -77,16 +72,5 @@ void matrix_init_kb(void) {
 	// put your keyboard start-up code here
 	// runs once when the firmware starts up
 	matrix_init_user();
-	uart_init();
 	led_init();
 }
-
-void matrix_scan_kb(void) {
-	// put your looping keyboard code here
-	// runs every cycle (a lot)
-	matrix_scan_user();
-}
-
-void led_set_kb(uint8_t usb_led) {
-
-}
diff --git a/keyboards/honeycomb/matrix.c b/keyboards/honeycomb/matrix.c
index a06afb6d968..2bed690689c 100755
--- a/keyboards/honeycomb/matrix.c
+++ b/keyboards/honeycomb/matrix.c
@@ -30,6 +30,7 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 #include "honeycomb.h"
 #include "pointing_device.h"
 #include "report.h"
+#include "protocol/serial.h"
 
 #if (MATRIX_COLS <= 8)
 # define print_matrix_header()  print("\nr/c 01234567\n")
@@ -94,12 +95,11 @@ uint8_t matrix_cols(void) {
 void matrix_init(void) {
 
     matrix_init_quantum();
+    serial_init();
 }
 
 uint8_t matrix_scan(void)
 {
-    SERIAL_UART_INIT();
-
     uint32_t timeout = 0;
 
     // The 's' character requests the RF slave to send the matrix
diff --git a/keyboards/honeycomb/rules.mk b/keyboards/honeycomb/rules.mk
index 19852d7ec3f..d6f98125eed 100755
--- a/keyboards/honeycomb/rules.mk
+++ b/keyboards/honeycomb/rules.mk
@@ -30,9 +30,4 @@ UNICODE_ENABLE = YES 		# Unicode
 # BLUETOOTH_ENABLE = yes # Enable Bluetooth with the Adafruit EZ-Key HID
 
 # # project specific files
-SRC += matrix.c
-
-USB = /dev/ttyACM0
-
-#upload: build
-#	$(honeycomb_UPLOAD_COMMAND)
+SRC += matrix.c serial_uart.c
diff --git a/keyboards/mitosis/config.h b/keyboards/mitosis/config.h
index b4499d0d6c5..0e089269e8b 100644
--- a/keyboards/mitosis/config.h
+++ b/keyboards/mitosis/config.h
@@ -60,19 +60,11 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 
 //UART settings for communication with the RF microcontroller
 #define SERIAL_UART_BAUD 1000000
-#define SERIAL_UART_DATA UDR1
-#define SERIAL_UART_UBRR (F_CPU / (16UL * SERIAL_UART_BAUD) - 1)
-#define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
 #define SERIAL_UART_RXD_PRESENT (UCSR1A & _BV(RXC1))
-#define SERIAL_UART_INIT() do { \
-    	/* baud rate */ \
-    	UBRR1L = SERIAL_UART_UBRR; \
-    	/* baud rate */ \
-    	UBRR1H = SERIAL_UART_UBRR >> 8; \
-    	/* enable TX and RX */ \
-    	UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
-    	/* 8-bit data */ \
-    	UCSR1C = _BV(UCSZ11) | _BV(UCSZ10); \
-  	} while(0)
+#define SERIAL_UART_INIT_CUSTOM       \
+    /* enable TX and RX */            \
+    UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
+    /* 8-bit data */                  \
+    UCSR1C = _BV(UCSZ11) | _BV(UCSZ10);
 
 #endif
diff --git a/keyboards/mitosis/matrix.c b/keyboards/mitosis/matrix.c
index e149b68bd7d..717a810678f 100644
--- a/keyboards/mitosis/matrix.c
+++ b/keyboards/mitosis/matrix.c
@@ -26,6 +26,7 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 #include "util.h"
 #include "matrix.h"
 #include "timer.h"
+#include "protocol/serial.h"
 
 #if (MATRIX_COLS <= 8)
 #    define print_matrix_header()  print("\nr/c 01234567\n")
@@ -79,12 +80,11 @@ uint8_t matrix_cols(void) {
 void matrix_init(void) {
 
     matrix_init_quantum();
+    serial_init();
 }
 
 uint8_t matrix_scan(void)
 {
-    SERIAL_UART_INIT();
-
     uint32_t timeout = 0;
 
     //the s character requests the RF slave to send the matrix
diff --git a/keyboards/mitosis/mitosis.c b/keyboards/mitosis/mitosis.c
index 1ca7276e410..50b6d8452f5 100644
--- a/keyboards/mitosis/mitosis.c
+++ b/keyboards/mitosis/mitosis.c
@@ -1,9 +1,5 @@
 #include "mitosis.h"
 
-void uart_init(void) {
-	SERIAL_UART_INIT();
-}
-
 void led_init(void) {
 	DDRD  |= (1<<1); // Pin to green, set as output
 	PORTD |= (1<<1); // Turn it off
@@ -15,7 +11,6 @@ void matrix_init_kb(void) {
 	// put your keyboard start-up code here
 	// runs once when the firmware starts up
 	matrix_init_user();
-	uart_init();
 	led_init();
 }
 
diff --git a/keyboards/mitosis/rules.mk b/keyboards/mitosis/rules.mk
index 466987e8c1e..4cb6d8c9b4f 100644
--- a/keyboards/mitosis/rules.mk
+++ b/keyboards/mitosis/rules.mk
@@ -28,14 +28,5 @@ NKRO_ENABLE = yes		# USB Nkey Rollover - not yet supported in LUFA
 UNICODE_ENABLE = yes 		# Unicode
 # BLUETOOTH_ENABLE = yes # Enable Bluetooth with the Adafruit EZ-Key HID
 
-USB = /dev/ttyACM0
-
-# upload: build
-# 	$(MITOSIS_UPLOAD_COMMAND)
-
-OPT_DEFS += -DMITOSIS_PROMICRO
-MITOSIS_UPLOAD_COMMAND = while [ ! -r $(USB) ]; do sleep 1; done; \
-                         avrdude -p $(MCU) -c avr109 -U flash:w:$(TARGET).hex -P $(USB)
-
 # # project specific files
-SRC = matrix.c
+SRC += matrix.c serial_uart.c
diff --git a/keyboards/planck/keymaps/thermal_printer/config.h b/keyboards/planck/keymaps/thermal_printer/config.h
index 4460cdbbe29..4ae9ced2581 100644
--- a/keyboards/planck/keymaps/thermal_printer/config.h
+++ b/keyboards/planck/keymaps/thermal_printer/config.h
@@ -3,22 +3,7 @@
 
 #include "../../config.h"
 
-#      define SERIAL_UART_BAUD 19200
-#      define SERIAL_UART_DATA UDR1
-#      define SERIAL_UART_UBRR (F_CPU / (16UL * SERIAL_UART_BAUD) - 1)
-#      define SERIAL_UART_RXD_VECT USART1_RX_vect
-#      define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
-#      define SERIAL_UART_INIT() do { \
-            /* baud rate */ \
-            UBRR1L = SERIAL_UART_UBRR; \
-            /* baud rate */ \
-            UBRR1H = SERIAL_UART_UBRR >> 8; \
-            /* enable TX */ \
-            UCSR1B = _BV(TXEN1); \
-            /* 8-bit data */ \
-            UCSR1C = _BV(UCSZ11) | _BV(UCSZ10); \
-            sei(); \
-        } while(0)
+#define SERIAL_UART_BAUD 19200
 
 /*
  * MIDI options
diff --git a/keyboards/redox_w/config.h b/keyboards/redox_w/config.h
index 1f40a694daf..b480b072f99 100644
--- a/keyboards/redox_w/config.h
+++ b/keyboards/redox_w/config.h
@@ -58,17 +58,9 @@
 
 //UART settings for communication with the RF microcontroller
 #define SERIAL_UART_BAUD 1000000
-#define SERIAL_UART_DATA UDR1
-#define SERIAL_UART_UBRR (F_CPU / (16UL * SERIAL_UART_BAUD) - 1)
-#define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
 #define SERIAL_UART_RXD_PRESENT (UCSR1A & _BV(RXC1))
-#define SERIAL_UART_INIT() do { \
-    	/* baud rate */ \
-    	UBRR1L = SERIAL_UART_UBRR; \
-    	/* baud rate */ \
-    	UBRR1H = SERIAL_UART_UBRR >> 8; \
-    	/* enable TX and RX */ \
-    	UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
-    	/* 8-bit data */ \
-    	UCSR1C = _BV(UCSZ11) | _BV(UCSZ10); \
-  	} while(0)
+#define SERIAL_UART_INIT_CUSTOM       \
+    /* enable TX and RX */            \
+    UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
+    /* 8-bit data */                  \
+    UCSR1C = _BV(UCSZ11) | _BV(UCSZ10);
diff --git a/keyboards/redox_w/matrix.c b/keyboards/redox_w/matrix.c
index 31233af1018..15ca66e34d2 100644
--- a/keyboards/redox_w/matrix.c
+++ b/keyboards/redox_w/matrix.c
@@ -24,6 +24,7 @@
 #include "util.h"
 #include "matrix.h"
 #include "timer.h"
+#include "protocol/serial.h"
 
 #if (MATRIX_COLS <= 8)
 #    define print_matrix_header()  print("\nr/c 01234567\n")
@@ -86,12 +87,11 @@ uint8_t matrix_cols(void) {
 void matrix_init(void) {
 
     matrix_init_quantum();
+    serial_init();
 }
 
 uint8_t matrix_scan(void)
 {
-    SERIAL_UART_INIT();
-
     uint32_t timeout = 0;
 
     //the s character requests the RF slave to send the matrix
diff --git a/keyboards/redox_w/redox_w.c b/keyboards/redox_w/redox_w.c
index 75df91066cd..05fa3395717 100644
--- a/keyboards/redox_w/redox_w.c
+++ b/keyboards/redox_w/redox_w.c
@@ -1,9 +1,5 @@
 #include "redox_w.h"
 
-void uart_init(void) {
-	SERIAL_UART_INIT();
-}
-
 void led_init(void) {
 	DDRD  |= (1<<1);
 	PORTD |= (1<<1);
@@ -16,20 +12,9 @@ void matrix_init_kb(void) {
 	// put your keyboard start-up code here
 	// runs once when the firmware starts up
 	matrix_init_user();
-	uart_init();
 	led_init();
 }
 
-void matrix_scan_kb(void) {
-	// put your looping keyboard code here
-	// runs every cycle (a lot)
-	matrix_scan_user();
-}
-
-void led_set_kb(uint8_t usb_led) {
-
-}
-
 #ifdef ONEHAND_ENABLE
 __attribute__ ((weak))
 const keypos_t hand_swap_config[MATRIX_ROWS][MATRIX_COLS] = {
diff --git a/keyboards/redox_w/rules.mk b/keyboards/redox_w/rules.mk
index 8b171f717b0..01d5c3c70ce 100644
--- a/keyboards/redox_w/rules.mk
+++ b/keyboards/redox_w/rules.mk
@@ -28,14 +28,5 @@ NKRO_ENABLE = yes		# USB Nkey Rollover - not yet supported in LUFA
 UNICODE_ENABLE = YES 		# Unicode
 # BLUETOOTH_ENABLE = yes # Enable Bluetooth with the Adafruit EZ-Key HID
 
-USB = /dev/ttyACM0
-
-OPT_DEFS += -DREDOX_W_PROMICRO
-INTERPHASE_UPLOAD_COMMAND = while [ ! -r $(USB) ]; do sleep 1; done; \
-                         avrdude -p $(MCU) -c avr109 -U flash:w:$(TARGET).hex -P $(USB)
-
 # # project specific files
-SRC = matrix.c
-
-# upload: build
-# 	$(REDOX_W_UPLOAD_COMMAND)
+SRC += matrix.c serial_uart.c
diff --git a/keyboards/sirius/uni660/rev1/config.h b/keyboards/sirius/uni660/rev1/config.h
index 98269d4261e..91d7c5d7a3a 100644
--- a/keyboards/sirius/uni660/rev1/config.h
+++ b/keyboards/sirius/uni660/rev1/config.h
@@ -59,19 +59,11 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 
 //UART settings for communication with the RF microcontroller
 #define SERIAL_UART_BAUD 1000000
-#define SERIAL_UART_DATA UDR1
-#define SERIAL_UART_UBRR (F_CPU / (16UL * SERIAL_UART_BAUD) - 1)
-#define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
 #define SERIAL_UART_RXD_PRESENT (UCSR1A & _BV(RXC1))
-#define SERIAL_UART_INIT() do { \
-    /* baud rate */ \
-    UBRR1L = SERIAL_UART_UBRR; \
-    /* baud rate */ \
-    UBRR1H = SERIAL_UART_UBRR >> 8; \
-    /* enable TX and RX */ \
+#define SERIAL_UART_INIT_CUSTOM       \
+    /* enable TX and RX */            \
     UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
-    /* 8-bit data */ \
-    UCSR1C = _BV(UCSZ11) | _BV(UCSZ10); \
-} while (0)
+    /* 8-bit data */                  \
+    UCSR1C = _BV(UCSZ11) | _BV(UCSZ10);
 
 #define DYNAMIC_KEYMAP_LAYER_COUNT 4
diff --git a/keyboards/sirius/uni660/rev1/matrix.c b/keyboards/sirius/uni660/rev1/matrix.c
index 3e231b33bc3..355fa7e5e91 100644
--- a/keyboards/sirius/uni660/rev1/matrix.c
+++ b/keyboards/sirius/uni660/rev1/matrix.c
@@ -27,6 +27,7 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 #include "matrix.h"
 #include "timer.h"
 #include "debounce.h"
+#include "protocol/serial.h"
 
 #if (MATRIX_COLS <= 8)
 #    define print_matrix_header()  print("\nr/c 01234567\n")
@@ -80,14 +81,13 @@ uint8_t matrix_cols(void) {
 void matrix_init(void) {
     debounce_init(MATRIX_ROWS);
     matrix_init_quantum();
+    serial_init();
 }
 
 uint8_t matrix_scan(void)
 {
     bool matrix_has_changed = false;
 
-    SERIAL_UART_INIT();
-
     uint32_t timeout = 0;
 
     //the s character requests the RF slave to send the matrix
diff --git a/keyboards/sirius/uni660/rev1/rev1.c b/keyboards/sirius/uni660/rev1/rev1.c
index 872004355e8..d4adac24b57 100644
--- a/keyboards/sirius/uni660/rev1/rev1.c
+++ b/keyboards/sirius/uni660/rev1/rev1.c
@@ -1,9 +1,5 @@
 #include "rev1.h"
 
-void uart_init(void) {
-    SERIAL_UART_INIT();
-}
-
 void led_init(void) {
     setPinOutput(D1); // Pin to green, set as output
     writePinHigh(D1); // Turn it off
@@ -17,7 +13,6 @@ void matrix_init_kb(void) {
     // put your keyboard start-up code here
     // runs once when the firmware starts up
     matrix_init_user();
-    uart_init();
     led_init();
 }
 
diff --git a/keyboards/sirius/uni660/rev2/ansi/config.h b/keyboards/sirius/uni660/rev2/ansi/config.h
index 7bca743633f..13e33ebf118 100644
--- a/keyboards/sirius/uni660/rev2/ansi/config.h
+++ b/keyboards/sirius/uni660/rev2/ansi/config.h
@@ -59,19 +59,11 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 
 //UART settings for communication with the RF microcontroller
 #define SERIAL_UART_BAUD 1000000
-#define SERIAL_UART_DATA UDR1
-#define SERIAL_UART_UBRR (F_CPU / (16UL * SERIAL_UART_BAUD) - 1)
-#define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
 #define SERIAL_UART_RXD_PRESENT (UCSR1A & _BV(RXC1))
-#define SERIAL_UART_INIT() do { \
-    /* baud rate */ \
-    UBRR1L = SERIAL_UART_UBRR; \
-    /* baud rate */ \
-    UBRR1H = SERIAL_UART_UBRR >> 8; \
-    /* enable TX and RX */ \
+#define SERIAL_UART_INIT_CUSTOM       \
+    /* enable TX and RX */            \
     UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
-    /* 8-bit data */ \
-    UCSR1C = _BV(UCSZ11) | _BV(UCSZ10); \
-} while (0)
+    /* 8-bit data */                  \
+    UCSR1C = _BV(UCSZ11) | _BV(UCSZ10);
 
 #define DYNAMIC_KEYMAP_LAYER_COUNT 4
diff --git a/keyboards/sirius/uni660/rev2/iso/config.h b/keyboards/sirius/uni660/rev2/iso/config.h
index 0cbbe0c5ba4..3283f0cd677 100644
--- a/keyboards/sirius/uni660/rev2/iso/config.h
+++ b/keyboards/sirius/uni660/rev2/iso/config.h
@@ -59,19 +59,11 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 
 //UART settings for communication with the RF microcontroller
 #define SERIAL_UART_BAUD 1000000
-#define SERIAL_UART_DATA UDR1
-#define SERIAL_UART_UBRR (F_CPU / (16UL * SERIAL_UART_BAUD) - 1)
-#define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
 #define SERIAL_UART_RXD_PRESENT (UCSR1A & _BV(RXC1))
-#define SERIAL_UART_INIT() do { \
-    /* baud rate */ \
-    UBRR1L = SERIAL_UART_UBRR; \
-    /* baud rate */ \
-    UBRR1H = SERIAL_UART_UBRR >> 8; \
-    /* enable TX and RX */ \
+#define SERIAL_UART_INIT_CUSTOM       \
+    /* enable TX and RX */            \
     UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
-    /* 8-bit data */ \
-    UCSR1C = _BV(UCSZ11) | _BV(UCSZ10); \
-} while (0)
+    /* 8-bit data */                  \
+    UCSR1C = _BV(UCSZ11) | _BV(UCSZ10);
 
 #define DYNAMIC_KEYMAP_LAYER_COUNT 4
diff --git a/keyboards/sirius/uni660/rev2/matrix.c b/keyboards/sirius/uni660/rev2/matrix.c
index 3e231b33bc3..355fa7e5e91 100644
--- a/keyboards/sirius/uni660/rev2/matrix.c
+++ b/keyboards/sirius/uni660/rev2/matrix.c
@@ -27,6 +27,7 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 #include "matrix.h"
 #include "timer.h"
 #include "debounce.h"
+#include "protocol/serial.h"
 
 #if (MATRIX_COLS <= 8)
 #    define print_matrix_header()  print("\nr/c 01234567\n")
@@ -80,14 +81,13 @@ uint8_t matrix_cols(void) {
 void matrix_init(void) {
     debounce_init(MATRIX_ROWS);
     matrix_init_quantum();
+    serial_init();
 }
 
 uint8_t matrix_scan(void)
 {
     bool matrix_has_changed = false;
 
-    SERIAL_UART_INIT();
-
     uint32_t timeout = 0;
 
     //the s character requests the RF slave to send the matrix
diff --git a/keyboards/sirius/uni660/rev2/rev2.c b/keyboards/sirius/uni660/rev2/rev2.c
index e19240ccc35..048495b9928 100644
--- a/keyboards/sirius/uni660/rev2/rev2.c
+++ b/keyboards/sirius/uni660/rev2/rev2.c
@@ -1,9 +1,5 @@
 #include "rev2.h"
 
-void uart_init(void) {
-    SERIAL_UART_INIT();
-}
-
 void led_init(void) {
     setPinOutput(D1); // Pin to green, set as output
     writePinHigh(D1); // Turn it off
@@ -17,7 +13,6 @@ void matrix_init_kb(void) {
     // put your keyboard start-up code here
     // runs once when the firmware starts up
     matrix_init_user();
-    uart_init();
     led_init();
 }
 
diff --git a/keyboards/telophase/config.h b/keyboards/telophase/config.h
index e9329c5736c..c67dd939bff 100644
--- a/keyboards/telophase/config.h
+++ b/keyboards/telophase/config.h
@@ -60,19 +60,11 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 
 //UART settings for communication with the RF microcontroller
 #define SERIAL_UART_BAUD 1000000
-#define SERIAL_UART_DATA UDR1
-#define SERIAL_UART_UBRR (F_CPU / (16UL * SERIAL_UART_BAUD) - 1)
-#define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
 #define SERIAL_UART_RXD_PRESENT (UCSR1A & _BV(RXC1))
-#define SERIAL_UART_INIT() do { \
-    	/* baud rate */ \
-    	UBRR1L = SERIAL_UART_UBRR; \
-    	/* baud rate */ \
-    	UBRR1H = SERIAL_UART_UBRR >> 8; \
-    	/* enable TX and RX */ \
-    	UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
-    	/* 8-bit data */ \
-    	UCSR1C = _BV(UCSZ11) | _BV(UCSZ10); \
-  	} while(0)
+#define SERIAL_UART_INIT_CUSTOM       \
+    /* enable TX and RX */            \
+    UCSR1B = _BV(TXEN1) | _BV(RXEN1); \
+    /* 8-bit data */                  \
+    UCSR1C = _BV(UCSZ11) | _BV(UCSZ10);
 
 #endif
diff --git a/keyboards/telophase/matrix.c b/keyboards/telophase/matrix.c
index c332eba556c..8edfce62d2a 100644
--- a/keyboards/telophase/matrix.c
+++ b/keyboards/telophase/matrix.c
@@ -26,6 +26,7 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 #include "util.h"
 #include "matrix.h"
 #include "timer.h"
+#include "protocol/serial.h"
 
 #if (MATRIX_COLS <= 8)
 #    define print_matrix_header()  print("\nr/c 01234567\n")
@@ -88,12 +89,11 @@ uint8_t matrix_cols(void) {
 void matrix_init(void) {
 
     matrix_init_quantum();
+    serial_init();
 }
 
 uint8_t matrix_scan(void)
 {
-    SERIAL_UART_INIT();
-
     uint32_t timeout = 0;
 
     //the s character requests the RF slave to send the matrix
diff --git a/keyboards/telophase/rules.mk b/keyboards/telophase/rules.mk
index f2ac0adb6c7..65cac9364b8 100644
--- a/keyboards/telophase/rules.mk
+++ b/keyboards/telophase/rules.mk
@@ -27,20 +27,13 @@ NKRO_ENABLE = yes		# USB Nkey Rollover - not yet supported in LUFA
 # MIDI_ENABLE = YES 		# MIDI controls
 UNICODE_ENABLE = YES 		# Unicode
 # BLUETOOTH_ENABLE = yes # Enable Bluetooth with the Adafruit EZ-Key HID
-LAYOUTS = ortho_4x12
-USB = /dev/ttyACM0
-
-# upload: build
-# 	$(MITOSIS_UPLOAD_COMMAND)
-
-OPT_DEFS += -DMITOSIS_PROMICRO
-MITOSIS_UPLOAD_COMMAND = while [ ! -r $(USB) ]; do sleep 1; done; \
-                         avrdude -p $(MCU) -c avr109 -U flash:w:$(TARGET).hex -P $(USB)
 
 # # project specific files
-SRC = matrix.c
+SRC = matrix.c serial_uart.c
 
 # Disable unsupported hardware
 RGBLIGHT_SUPPORTED = no
 AUDIO_SUPPORTED = no
 BACKLIGHT_SUPPORTED = no
+
+LAYOUTS = ortho_4x12
diff --git a/keyboards/telophase/telophase.c b/keyboards/telophase/telophase.c
index c77a43389f4..0e04debeb80 100644
--- a/keyboards/telophase/telophase.c
+++ b/keyboards/telophase/telophase.c
@@ -1,9 +1,5 @@
 #include "telophase.h"
 
-void uart_init(void) {
-	SERIAL_UART_INIT();
-}
-
 void led_init(void) {
 	DDRD  |= (1<<1);
 	PORTD |= (1<<1);
@@ -16,20 +12,9 @@ void matrix_init_kb(void) {
 	// put your keyboard start-up code here
 	// runs once when the firmware starts up
 	matrix_init_user();
-	uart_init();
 	led_init();
 }
 
-void matrix_scan_kb(void) {
-	// put your looping keyboard code here
-	// runs every cycle (a lot)
-	matrix_scan_user();
-}
-
-void led_set_kb(uint8_t usb_led) {
-
-}
-
 #ifdef SWAP_HANDS_ENABLE
 __attribute__ ((weak))
 const keypos_t hand_swap_config[MATRIX_ROWS][MATRIX_COLS] = {
diff --git a/quantum/config_common.h b/quantum/config_common.h
index 2d9c70b08de..5973232ef62 100644
--- a/quantum/config_common.h
+++ b/quantum/config_common.h
@@ -367,51 +367,6 @@
 #    endif
 #endif
 
-/* USART configuration */
-#ifdef BLUETOOTH_ENABLE
-#    ifdef __AVR_ATmega32U4__
-#        define SERIAL_UART_BAUD 9600
-#        define SERIAL_UART_DATA UDR1
-#        define SERIAL_UART_UBRR (F_CPU / (16UL * SERIAL_UART_BAUD) - 1)
-#        define SERIAL_UART_RXD_VECT USART1_RX_vect
-#        define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
-#        define SERIAL_UART_INIT()                  \
-            do {                                    \
-                /* baud rate */                     \
-                UBRR1L = SERIAL_UART_UBRR;          \
-                /* baud rate */                     \
-                UBRR1H = SERIAL_UART_UBRR >> 8;     \
-                /* enable TX */                     \
-                UCSR1B = _BV(TXEN1);                \
-                /* 8-bit data */                    \
-                UCSR1C = _BV(UCSZ11) | _BV(UCSZ10); \
-                sei();                              \
-            } while (0)
-#    elif defined(__AVR_AT90USB646__) || defined(__AVR_AT90USB647__) || defined(__AVR_AT90USB1286__) || defined(__AVR_AT90USB1287__)
-#        define SERIAL_UART_BAUD 115200
-#        define SERIAL_UART_DATA UDR1
-/* UBRR should result in ~16 and set UCSR1A = _BV(U2X1) as per rn42 documentation. HC05 needs baudrate configured accordingly */
-#        define SERIAL_UART_UBRR (F_CPU / (8UL * SERIAL_UART_BAUD) - 1)
-#        define SERIAL_UART_RXD_VECT USART1_RX_vect
-#        define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
-#        define SERIAL_UART_INIT()                  \
-            do {                                    \
-                UCSR1A = _BV(U2X1);                 \
-                /* baud rate */                     \
-                UBRR1L = SERIAL_UART_UBRR;          \
-                /* baud rate */                     \
-                UBRR1H = SERIAL_UART_UBRR >> 8;     \
-                /* enable TX */                     \
-                UCSR1B = _BV(TXEN1);                \
-                /* 8-bit data */                    \
-                UCSR1C = _BV(UCSZ11) | _BV(UCSZ10); \
-                sei();                              \
-            } while (0)
-#    else
-#        error "USART configuration is needed."
-#    endif
-#endif
-
 #define API_SYSEX_MAX_SIZE 32
 
 #include "song_list.h"
diff --git a/tmk_core/protocol/serial.h b/tmk_core/protocol/serial.h
index b70d117d7c7..0204b84a921 100644
--- a/tmk_core/protocol/serial.h
+++ b/tmk_core/protocol/serial.h
@@ -37,6 +37,8 @@ POSSIBILITY OF SUCH DAMAGE.
 
 #pragma once
 
+#define SERIAL_UART_DATA UDR1
+
 /* host role */
 void    serial_init(void);
 uint8_t serial_recv(void);
diff --git a/tmk_core/protocol/serial_uart.c b/tmk_core/protocol/serial_uart.c
index a15124193af..4fe059e7d9d 100644
--- a/tmk_core/protocol/serial_uart.c
+++ b/tmk_core/protocol/serial_uart.c
@@ -40,6 +40,22 @@ POSSIBILITY OF SUCH DAMAGE.
 #include <avr/interrupt.h>
 #include "serial.h"
 
+#ifndef SERIAL_UART_BAUD
+#    define SERIAL_UART_BAUD 9600
+#endif
+
+#define SERIAL_UART_UBRR (F_CPU / (16UL * SERIAL_UART_BAUD) - 1)
+#define SERIAL_UART_TXD_READY (UCSR1A & _BV(UDRE1))
+#define SERIAL_UART_RXD_VECT USART1_RX_vect
+
+#ifndef SERIAL_UART_INIT_CUSTOM
+#    define SERIAL_UART_INIT_CUSTOM \
+    /* enable TX */                 \
+    UCSR1B = _BV(TXEN1);            \
+    /* 8-bit data */                \
+    UCSR1C = _BV(UCSZ11) | _BV(UCSZ10);
+#endif
+
 #if defined(SERIAL_UART_RTS_LO) && defined(SERIAL_UART_RTS_HI)
 // Buffer state
 //   Empty:           RBUF_SPACE == RBUF_SIZE(head==tail)
@@ -61,7 +77,14 @@ POSSIBILITY OF SUCH DAMAGE.
 #    define rbuf_check_rts_hi()
 #endif
 
-void serial_init(void) { SERIAL_UART_INIT(); }
+void serial_init(void) {
+    do {
+        // Set baud rate
+        UBRR1L = SERIAL_UART_UBRR;
+        UBRR1L = SERIAL_UART_UBRR >> 8;
+        SERIAL_UART_INIT_CUSTOM;
+    } while (0);
+}
 
 // RX ring buffer
 #define RBUF_SIZE 256